|
| Status |
Public on Jan 24, 2010 |
| Title |
Transcriptome of the Nxnl1-/- mouse retina |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Rod-derived Cone Viability Factor (RdCVF, alias nxnl1) is a retina-specific protein identified for its therapeutic potential in supporting cone survival during retinal degeneration.
A nxnl1 knockout mouse model was created and the transcriptome used to demonstrate that the retina is compromised by the absence of nxnl1.
Keywords: genetic modification, transcription-profile, retina
|
| |
|
| Overall design |
In total 9 samples were analyzed, they represent three different genotypes (wt/wt, ko/wt, ko/ko) that were tested in triplicate each.
|
| |
|
| Contributor(s) |
Cronin T, Raffelsberger W, Lee-Rivera I, Kinzel B, Clerin E, Poch O, Sahel J, Leveillard T |
| Citation(s) |
20139892 |
| |
| Submission date |
Dec 08, 2008 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Wolfgang Raffelsberger |
| E-mail(s) |
w.raffelsberger@unistra.fr
|
| Organization name |
IGBMC
|
| Department |
DBGS
|
| Lab |
LBGI
|
| Street address |
1 rue Laurent Fries
|
| City |
Illkirch/Strasbourg |
| ZIP/Postal code |
67404 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA110473 |
Less...
More...