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Series GSE138485 Query DataSets for GSE138485
Status Public on Oct 08, 2019
Title Retrospective gene expression analysis of human RNA samples from Hepatocellular Carcinoma in relation with survival
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary The aim of this study is to identify by Next Generation Sequencing - RNA-seq profiling a molecular signature of Hepatocellular Carcinoma samples that correlates with survival. The samples were retrospectively derived from hepatocellular carcinoma tissue as well as non-tumor tissue from the livers of the same patients. The bioinformatical analysis of 23 pairs RNA-seq datasets were obtained from human RNAs on Illumina Hiseq-PE150. Due to the lack of biological sample duplication, this datasets were used hisat2 2.1.0 and gfold v1.1.4 for expression analysis to identify differences in gene expression between tumors and adjacent tissues. (including up- and down-regulation).
Overall design mRNA profiles of 23 pairs of hepatocellular carcinoma tissue as well as non-tumor tissue from the livers of the same patients were generated by Next Generation Sequencing - RNA-seq, using Illumina Hiseq-PE150.
Contributor(s) Huang H, Zheng S
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Submission date Oct 07, 2019
Last update date Oct 10, 2019
Contact name Hechen Huang
Organization name First Affiliated Hospital, School of Medicine, Zhejiang University
Department Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery
Lab NHFPC Key Laboratory of Combined Multi-organ Transplantation
Street address 79 Qingchun Road
City Hangzhou
State/province Zhejiang
ZIP/Postal code 310003
Country China
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (46)
GSM4109609 Tumor T_A_004
GSM4109610 Tumor T_B_005
GSM4109611 Tumor T_C_007
BioProject PRJNA576155
SRA SRP224575

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Supplementary file Size Download File type/resource
GSE138485_RAW.tar 80.3 Mb (http)(custom) TAR (of XLS)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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