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Series GSE137492 Query DataSets for GSE137492
Status Public on Sep 17, 2019
Title Dissecting the dynamics of signaling events in the BMP,WNT and NODAL cascade during self-organized fate patterning in human gastruloids
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary To determine the in vivo cellular identity of BMP-treated human embryonic stem cells (hESCs), we performed bulk RNA sequencing data of hESCs under pluripotency and BMP-treated conditions. Our analyses show that BMP-treated hESCs resemble human trophoblast cells in vivo.
 
Overall design mRNA profiles of four different samples, each with two biological replicates. Samples: 1) hESCs in mTeSR1 for 48h, 2) hESCs in mTeSR1+BMP4 for 48h, 3) hESCs in mTeSR1+BMP4+IWP2 for 48h, 4) hESCs in mTeSR1+BMP4+SB for 48h
 
Contributor(s) Chhabra S, Liu L, Goh R, Kong X, Warmflash A
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Submission date Sep 16, 2019
Last update date Sep 17, 2019
Contact name Aryeh Warmflash
E-mail(s) aw21@rice.edu
Phone 7133482456
Organization name Rice University
Street address 6100 Main St
City Houston
State/province TX
ZIP/Postal code 77005
Country USA
 
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (8)
GSM4080163 media_1
GSM4080164 media_2
GSM4080165 bmp_1
Relations
BioProject PRJNA565722
SRA SRP221734

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE137492_SupplementaryTable1.xlsx 2.0 Mb (ftp)(http) XLSX
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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