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Series GSE137408 Query DataSets for GSE137408
Status Public on Nov 26, 2019
Title Splicing and gene expression changes in human MDAM-MB231 breast cancer cells with TRA2B knockdown
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary RNA-seq data from human MDA-MB231 breast cancer cells expressing control or TRA2B-targeting shRNAs grown for 8 days in 3D culture in matrigel
 
Overall design We examined the differential gene expression and splicing changes in MDA-MB231 cells expressing a DOX-inducible non targeting (shCTL) or TRA2B-targeting shRNA (TRA2Bsh1 and TRA2B sh2). For each shRNA, we compared -DOX vs +DOX.
 
Contributor(s) Anczukow O, Krainer AR
Citation(s) 31775037
Submission date Sep 13, 2019
Last update date Jan 08, 2020
Contact name Marina Yurieva
E-mail(s) marina.v.yurieva@gmail.com
Organization name Jackson Laboratory
Department Computational Sciences
Street address 10 Discovery dr
City Farmington
State/province Connecticut
ZIP/Postal code 06032
Country USA
 
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (18)
GSM4078695 TRA2B_shRNA2_-DOX_replicate_1
GSM4078696 TRA2B_shRNA2_-DOX_replicate_2
GSM4078697 TRA2B_shRNA2_-DOX_replicate_3
Relations
BioProject PRJNA565391
SRA SRP221583

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE137408_MDA-MB231_counts.txt.gz 1.1 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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