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| Status |
Public on Aug 26, 2022 |
| Title |
Assessment of the stabilty of Treg cell subsets in the bone marrow [targeted Bisulfite-seq] |
| Organism |
Mus musculus |
| Experiment type |
Methylation profiling by high throughput sequencing
|
| Summary |
We analyzed the methlation status of bone marrow conventional T cells, pTregs, tTregs, Tregs induced by bone marrow Aire-expressing cells, and in vitro-induced Tregs
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| |
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| Overall design |
6.5TCR (HA-specific CD4) T cells were transferred into Aire-HA host and bone marrow T cell subsets were sorted 14 days post transfer for comparison of their methylation status of TSDR and Treg-specific signature genes
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| |
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| Contributor(s) |
Chen C, Delacher M, Imbusch CD, Feuerer M, Beckhove P |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Sep 04, 2019 |
| Last update date |
Aug 27, 2022 |
| Contact name |
Philipp Beckhove |
| E-mail(s) |
philipp.beckhove@rcii.de
|
| Organization name |
Regensburg Center for Interventional Immunology
|
| Street address |
Franz-Josef-Strauss-Allee 11
|
| City |
Regensburg |
| ZIP/Postal code |
93053 |
| Country |
Germany |
| |
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| Platforms (1) |
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| Samples (15)
|
| GSM4060088 |
Bisulfite-seq_Donor 6.5TCR T cells which were not converted to Tregs, rep1 |
| GSM4060089 |
Bisulfite-seq_Donor 6.5TCR T cells which were not converted to Tregs, rep2 |
| GSM4060090 |
Bisulfite-seq_Donor 6.5TCR T cells which were not converted to Tregs, rep3 |
| GSM4060091 |
Bisulfite-seq_Donor 6.5TCR T cells which were converted to Tregs, rep1 |
| GSM4060092 |
Bisulfite-seq_Donor 6.5TCR T cells which were converted to Tregs, rep2 |
| GSM4060093 |
Bisulfite-seq_Donor 6.5TCR T cells which were converted to Tregs, rep3 |
| GSM4060094 |
Bisulfite-seq_in vitro-induced Tregs, rep1 |
| GSM4060095 |
Bisulfite-seq_in vitro-induced Tregs, rep2 |
| GSM4060096 |
Bisulfite-seq_in vitro-induced Tregs, rep3 |
| GSM4060097 |
Bisulfite-seq_Host pTregs, rep1 |
| GSM4060098 |
Bisulfite-seq_Host pTregs, rep2 |
| GSM4060099 |
Bisulfite-seq_Host pTregs, rep3 |
| GSM4060100 |
Bisulfite-seq_Host tTregs, rep1 |
| GSM4060101 |
Bisulfite-seq_Host tTregs, rep2 |
| GSM4060102 |
Bisulfite-seq_Host tTregs, rep3 |
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| This SubSeries is part of SuperSeries: |
| GSE136650 |
Induction of autoreactive regulatory T cells through promiscuous gene expression by bone marrow-resident Aire+ antigen-presenting cells |
|
| Relations |
| BioProject |
PRJNA563903 |
| SRA |
SRP220343 |
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