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Series GSE136105 Query DataSets for GSE136105
Status Public on Aug 22, 2019
Title Gene expression profiling in lung and breast cancer cells treated by Bloom-specific siRNAs
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary A549 and MDA-MB-231 cells were transfected with the Bloom-specific siRNA. Total RNA was extracted using Trizol at 48 hours after transfection. RNA-SEQ was carried out to profile the gene expression in both culture conditions.
Overall design The goal of this experiment was to profie the genes that are regulated by Bloom (BLM RecQ like helicase) in cancer cells. Gene expression was probed globally using RNA-SEQ.
Contributor(s) Shan B, Alsager S
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Submission date Aug 21, 2019
Last update date Aug 24, 2019
Contact name Bin Shan
Phone 015093587813
Organization name Washington State University
Department Biomedical Sciences
Street address 412 E Spokane Falls Blvd
City Spokane
State/province Washington
ZIP/Postal code 99202
Country USA
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (18)
GSM4041189 A549.BLM.siRNA1.1
GSM4041190 A549.BLM.siRNA1.2
GSM4041191 A549.BLM.siRNA1.3
BioProject PRJNA561309
SRA SRP218977

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE136105_RAW.tar 11.3 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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