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Status |
Public on Aug 07, 2019 |
Title |
RNA-sequencing of epicardial adipose tissue of patients with atrial fibrillation |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Accumulating studies have suggested that epicardial adipose tissue play an important role in the pathogenesis of atrial fibrillation (AF), but few have characterized the underlying mechanism between their interactions. Recent evidence suggested that bioactive molecules secreted from EAT, including exosomes carrying non-coding RNAs, may modulate atrial remodeling. The aim of the present study was to investigate the expression profile of mRNAs and ncRNAs in EAT with AF.
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Overall design |
Epicardial adipose samples collected from patients with persistent non-valvular AF (n=6) and sinus rhythm (n=6) were profiled using RNA-sequencing on the Illimina HiSeq 4000.
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Contributor(s) |
Zhao L, Yang X |
Citation(s) |
31731197 |
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Submission date |
Aug 06, 2019 |
Last update date |
Nov 17, 2022 |
Contact name |
Lei Zhao |
E-mail(s) |
lily885300@sina.com
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Organization name |
Beijing Chaoyang Hospital
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Street address |
Gongti Nanlu No.8
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City |
Beijing |
State/province |
Beijing |
ZIP/Postal code |
100020 |
Country |
China |
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Platforms (1) |
GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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Samples (12)
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GSM4009118 |
LSQ: persistent non-valvular atrial fibrillation (AF) |
GSM4009119 |
QP: persistent non-valvular atrial fibrillation (AF) |
GSM4009120 |
SHY: persistent non-valvular atrial fibrillation (AF) |
GSM4009121 |
SSF: sinus rhythm (control) |
GSM4009122 |
SYL: sinus rhythm (control) |
GSM4009123 |
THY: persistent non-valvular atrial fibrillation (AF) |
GSM4009124 |
XJQ: sinus rhythm (control) |
GSM4009125 |
XXX: persistent non-valvular atrial fibrillation (AF) |
GSM4009126 |
ZYQ: persistent non-valvular atrial fibrillation (AF) |
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Relations |
BioProject |
PRJNA558912 |
SRA |
SRP217534 |