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Series GSE135445 Query DataSets for GSE135445
Status Public on Aug 07, 2019
Title RNA-sequencing of epicardial adipose tissue of patients with atrial fibrillation
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Accumulating studies have suggested that epicardial adipose tissue play an important role in the pathogenesis of atrial fibrillation (AF), but few have characterized the underlying mechanism between their interactions. Recent evidence suggested that bioactive molecules secreted from EAT, including exosomes carrying non-coding RNAs, may modulate atrial remodeling. The aim of the present study was to investigate the expression profile of mRNAs and ncRNAs in EAT with AF.
 
Overall design Epicardial adipose samples collected from patients with persistent non-valvular AF (n=6) and sinus rhythm (n=6) were profiled using RNA-sequencing on the Illimina HiSeq 4000.
 
Contributor(s) Zhao L, Yang X
Citation(s) 31731197
Submission date Aug 06, 2019
Last update date Nov 17, 2022
Contact name Lei Zhao
E-mail(s) lily885300@sina.com
Organization name Beijing Chaoyang Hospital
Street address Gongti Nanlu No.8
City Beijing
State/province Beijing
ZIP/Postal code 100020
Country China
 
Platforms (1)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Samples (12)
GSM4009115 AGZ: sinus rhythm (control)
GSM4009116 BYP: sinus rhythm (control)
GSM4009117 LJ: sinus rhythm (control)
Relations
BioProject PRJNA558912
SRA SRP217534

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE135445_Expression_Gene.xlsx 2.7 Mb (ftp)(http) XLSX
GSE135445_Expression_Transcript.xlsx 6.5 Mb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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