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| Status |
Public on Aug 19, 2019 |
| Title |
scRNAseq transcriptome analysis of developing regulatory T cells and precursors in the thymus |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We analyzed the individual transcriptomes of thymic Treg cells (CD4+Foxp3+), their immediate precursors (CD25+CD4+Foxp3-) and mature CD4 single positive thymocytes (CD4+Foxp3-CD25-CD62L+CD24-).
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| Overall design |
To gain insight into characteristic features of thymocytes producing IL-2 in situ, single-cell RNA sequencing data was collected from mature CD25-Foxp3-CD4SP, CD25+Foxp3- and Foxp3+ CD4SP thymocytes.
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| Contributor(s) |
Hemmers S, Schizas M, Azizi E, Dikiy S, Zhong Y, Feng Y, Altan-Bonnet G, Rudensky AY |
| Citation(s) |
31434685 |
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| Submission date |
Jul 25, 2019 |
| Last update date |
Nov 21, 2019 |
| Contact name |
Elham Azizi |
| E-mail(s) |
elham.azizi@gmail.com
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| Organization name |
Memorial Sloan Kettering Cancer Center
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| Street address |
417 E 68th St Z1141
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| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10065 |
| Country |
USA |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA556716 |
| SRA |
SRP216429 |
