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| Status |
Public on Jul 07, 2020 |
| Title |
The landscape of H3K27me2 in mice zygotes |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
H3K27 di-methylation and H3K27 trimethylation are marks of facultative heterochromatin which maintains transcriptional repression established during early development in many eukaryotes. However, the mechanism underlying establishment and regulation of epigenetic asymmetry in the zygote remains obscure. Here we report the distribution pattern of H3K27me2 in Ezh2m+/p+ and Ezh2m-/p+ mice zygotes using the approach of ULI-NChIP.
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| |
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| Overall design |
ULI-NChIP profiling of H3K27me2 in Ezh2m+/p+ and Ezh2m-/p+ mice zygotes.
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| Contributor(s) |
Sun Q, Gao S, Wang Z, Ou X, Meng T, Liu X, Zhou Q, Zhao Z |
| Citation(s) |
33311485 |
| |
| Submission date |
Jul 21, 2019 |
| Last update date |
Dec 22, 2020 |
| Contact name |
Qingyuan Sun |
| E-mail(s) |
sunqy@ioz.ac.cn
|
| Phone |
8601064807050
|
| Organization name |
Institute of Zoology, Chinese Academy of Sciences
|
| Department |
State Key Laboratory of Stem Cell and Reproductive Biology
|
| Street address |
Beichen West Rd., Chaoyang
|
| City |
Beijing |
| State/province |
Beijing |
| ZIP/Postal code |
100101 |
| Country |
China |
| |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA555756 |
| SRA |
SRP215710 |
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