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Series GSE134366 Query DataSets for GSE134366
Status Public on Aug 19, 2019
Title Genome-wide analysis of chromatin accessibility in developing thymic Treg cells
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We analyzed open chromatin regions in thymic Treg cells, their immediate precursors (CD25+ Foxp3-), and mature and semi-mature CD4 single positive cells. We wished to understand which chromatin regions become accessible in response to TCR-stimulation and then Foxp3 expression as Treg cells develop.
 
Overall design Examination of chromatin accessibility in developing CD4SP thymocyte subsets, including Treg cells and immediate precursors
 
Contributor(s) Dikiy S, Feng Y, Zhong Y, Rudensky A
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Submission date Jul 16, 2019
Last update date Aug 21, 2019
Contact name Yi Zhong
E-mail(s) zhongy@cbio.mskcc.org
Organization name Memorial Sloan Kettering Cancer Center
Street address 417 East 68th Street
City New York
State/province NY
ZIP/Postal code 10065
Country USA
 
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (8)
GSM3943885 Treg precursor, wt_cd25_atac_r1
GSM3943886 Treg precursor, wt_cd25_atac_r2
GSM3943887 thymic Treg, wt_foxp3_atac_r1
Relations
BioProject PRJNA554863
SRA SRP214837

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE134366_RAW.tar 3.7 Mb (http)(custom) TAR (of CNT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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