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Series GSE128972 Query DataSets for GSE128972
Status Public on Mar 28, 2022
Title Expression data from human normal fibroblasts (NFs) and cancer associated fibroblasts (CAFs)
Platform organism synthetic construct
Sample organism Homo sapiens
Experiment type Non-coding RNA profiling by array
Summary CAFs are the major regulators in tumor microenviroment which promote cancer progression. We want to know which miRNAs changed in human CAFs compared to NFs.
We used microarrays to detail the mature miRNA expression and identified distinct classes of 2-fold changed miRNAs during this process.
 
Overall design NFs and CAFs were isolated from normal or bladder cancer tissues, respectively from 3 individuals. And cells were used for RNA extraction and hybridization on Affymetrix microarrays.
 
Contributor(s) Zhuang J, Yan J
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Submission date Mar 28, 2019
Last update date Mar 29, 2022
Contact name Junlong Zhuang
E-mail(s) zhuangjl-2008@163.com
Organization name Institute of Urology, Drum Tower hospital
Street address 321# Zhongshan Road
City Nanjing
ZIP/Postal code 210008
Country China
 
Platforms (1)
GPL19117 [miRNA-4] Affymetrix Multispecies miRNA-4 Array
Samples (6)
GSM3689314 CAF cells_rep1
GSM3689315 CAF cells_rep2
GSM3689316 CAF cells_rep3
Relations
BioProject PRJNA529597

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE128972_RAW.tar 4.3 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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