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| Status |
Public on Jun 10, 2020 |
| Title |
Single-cell RNA-seq of human peripheral blood NKT cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
NKT cells are potent immune regulators and skew immune responses toward either inflammation or tolerance through quickly secreting either T helper (Th)1-, Th2-, Th17- or regulatory T-associated cytokines upon activation. Although the thymic development and functional differentiation of NKT cells is well defined in mice, it has not yet been studied in detail in humans.
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| Overall design |
We performed single-cell RNA-sequencing (scRNA-seq) of unstimulated and PMA/ionomycin-stimulated NKT cells from human peripheral blood mononuclear cells (PBMCs).
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| Contributor(s) |
Wang J, Adrianto I, Wu X, Zhou L, Mi Q |
| Citation(s) |
32528956 |
| |
| Submission date |
Mar 13, 2019 |
| Last update date |
Aug 18, 2020 |
| Contact name |
Indra Adrianto |
| E-mail(s) |
iadrian1@hfhs.org
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| Phone |
313-874-5999
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| Organization name |
Henry Ford Health System
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| Department |
Public Health Sciences
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| Street address |
1 Ford Place
|
| City |
Detroit |
| State/province |
MI |
| ZIP/Postal code |
48202 |
| Country |
USA |
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| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA526874 |
| SRA |
SRP188375 |
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