|
| Status |
Public on May 12, 2020 |
| Title |
Heterogeneous Bach2 expression distinguishes rTreg cells and aTreg cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
These are the FastQ files used for RNA-Seq analysis of splenic Foxp3+ Treg cells that express either high or low levels of Bach2
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| |
|
| Overall design |
RNA-seq profile from single EGFP+ Treg cells isolated from the spleens of tamoxifen-treated Bach2+/+ Foxp3EGFP-Cre-ERT2 (WT) mice and Bach2fl/fl Foxp3EGFP-Cre-ERT2 (CKO) mice , were generated by deep sequencing using Illumina HiSeq2500
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| |
|
| Contributor(s) |
Sadiyah M |
| Citation(s) |
32515782 |
| Submission date |
Mar 01, 2019 |
| Last update date |
Aug 17, 2020 |
| Contact name |
Mohammed-Firas Sadiyah |
| E-mail(s) |
mfs37@cam.ac.uk
|
| Organization name |
University of Cambridge
|
| Street address |
The Old Schools, Trinity Ln
|
| City |
Cambridge |
| ZIP/Postal code |
CB2 1TN |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (8)
|
| GSM3636565 |
Foxp3-GFP+Treg_BACH2-RFP_HI_Female1_RNA-seq |
| GSM3636566 |
Foxp3-GFP+Treg_BACH2-RFP_HI_Female2_RNA-seq |
| GSM3636567 |
Foxp3-GFP+Treg_BACH2-RFP_HI_Male1_RNA-seq |
| GSM3636568 |
Foxp3-GFP+Treg_BACH2-RFP_HI_Male2_RNA-seq |
| GSM3636569 |
Foxp3-GFP+Treg_BACH2-RFP_LO_Female1_RNA-seq |
| GSM3636570 |
Foxp3-GFP+Treg_BACH2-RFP_LO_Female2_RNA-seq |
| GSM3636571 |
Foxp3-GFP+Treg_BACH2-RFP_LO_Male1_RNA-seq |
| GSM3636572 |
Foxp3-GFP+Treg_BACH2-RFP_LO_Male2_RNA-seq |
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| This SubSeries is part of SuperSeries: |
| GSE128176 |
BACH2 is repurposed following Treg lineage commitment to drive the functional quiescence and maintenance of resting Treg cells |
|
| Relations |
| BioProject |
PRJNA527354 |
| SRA |
SRP188608 |
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