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Series GSE126560 Query DataSets for GSE126560
Status Public on Jul 01, 2019
Title Effect of Rgnef knockout in an aggressive ovarian cancer cell line
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary CRISPR/Cas9-mediated Rgnef knockout was performed in the aggressive ID8-IPs (alternaate name is KMF cells). Gene expression profiles of Rgnef-/- or Rgnef-/- cells re-expressing GFP-Rgnef were generated. Differential downregulation of antioxidant genes was observed in Rgnef-/- cells. Results provide insight into the role of Rgnef in promoting ovarian tumor progression.
Overall design mRNA profiles of ID8-KMF Rgnef-/- or Rgnef-/- cell re-expressing GFP-Rgnef were generated in triplicate using an Illumina HiSeq 4000.
Contributor(s) Kleinschmidt EG, Miller NL, Ozmandenci D, Tancioni I, Diaz-Osterman C, Barrie AM, Taylor K, Ye A, Jiang S, Connolly DC, Stupack DG, Schlaepfer DD
Citation(s) 31308489
Submission date Feb 14, 2019
Last update date Oct 02, 2019
Contact name David D Schlaepfer
Phone 858822344
Organization name UCSD
Department Moores Cancer Center
Lab Gynecologic Oncology
Street address 3855 Health Sciences Dr.
City La Jolla
State/province CA
ZIP/Postal code 92093
Country USA
Platforms (1)
GPL21103 Illumina HiSeq 4000 (Mus musculus)
Samples (6)
GSM3604582 ID8IPGR1
GSM3604583 ID8IPGR2
GSM3604584 ID8IPGR3
BioProject PRJNA522374
SRA SRP185891

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Supplementary file Size Download File type/resource
GSE126560_processed_FPKM_data.txt.gz 719.0 Kb (ftp)(http) TXT
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Processed data are available on Series record

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