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| Status |
Public on Oct 21, 2019 |
| Title |
Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
14537 epithelial cells from adult human ileum, colon and rectum are performed single-cell transcriptome analysis, cell types and signature genes are presented, so as new representative genes. Bases on the gene expression pattern, difference of cell types, signaling changes, absorption funciton, inmmunity and hormone activity are analyzed. In addition, species diversity is briefly performed by analysis of human and mouse ileum single-cell database.
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| Overall design |
identify cell consititution and function difference of ileum, colon and rectum at single-cell level.
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| Contributor(s) |
Wang Y, Song W, Wang J, Wang T, Xiong X, Qi Z, Fu W, Yang X, Chen Y |
| Citation(s) |
31753849 |
| Submission date |
Jan 31, 2019 |
| Last update date |
Feb 24, 2021 |
| Contact name |
Ye-guang Chen |
| E-mail(s) |
ygchen@mail.tsinghua.edu.cn
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| Organization name |
Tsinghua University
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| Department |
School of life science
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| Lab |
Molcell
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| Street address |
Tsinghua Road, Medical Building
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| City |
Beijing |
| ZIP/Postal code |
100084 |
| Country |
China |
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| Platforms (1) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA518129 |
| SRA |
SRP183081 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE125970_cell_info.txt.gz |
85.9 Kb |
(ftp)(http) |
TXT |
| GSE125970_raw_UMIcounts.txt.gz |
35.8 Mb |
(ftp)(http) |
TXT |
| GSE125970_scale_data.txt.gz |
374.1 Mb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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