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Series GSE124704 Query DataSets for GSE124704
Status Public on Jul 16, 2019
Title Durable Response of Enzalutamide-resistant Prostate Cancer to Supraphysiological Testosterone Is Associated with a Multifaceted Growth Suppression and Impaired DNA Damage Response Transcriptomic Program in Patient-derived Xenografts
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary The study aims to determine SPT effect on the CRPC growth and molecular alterations using LuCaP PDX CRPC models.
 
Overall design RNA sequencing of castration-resistant PC (CRPC) patient-derived xenograft (PDX) lines using Illumina TruSeq Library prep and sequenced on Illumina HiSeq 2500.
 
Contributor(s) Lam H, Nguyen HM, Brown LG, Coleman IM, Gulati R, Lakely B, Sondheim D, Labrecque MP, Marck B, Matsumoto AM, Mostaghel EA, Nelson PS, Corey E
Citation(s) 31227306
Submission date Jan 06, 2019
Last update date Aug 13, 2019
Contact name Ilsa Coleman
E-mail(s) icoleman@fhcrc.org
Phone 206-667-1703
Organization name Fred Hutchinson Cancer Research Center
Department Human Biology
Lab Peter Nelson
Street address 1100 Fairview Ave N, E2-112
City Seattle
State/province WA
ZIP/Postal code 98109
Country USA
 
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (70)
GSM3543626 1_1546_4-1_35CR-ENZR_Control_EOS
GSM3543627 2_1546_4-4_35CR-ENZR_Control_EOS
GSM3543628 3_1546_4-5_35CR-ENZR_Control_EOS
Relations
BioProject PRJNA513162
SRA SRP175707

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE124704_RAW.tar 47.1 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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