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| Status |
Public on Dec 14, 2019 |
| Title |
microRNA expression profile in renal tissues of rats with doxorubicin nephropathy by Mongolian medicine Narenmandula |
| Platform organism |
synthetic construct |
| Sample organism |
Rattus norvegicus |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
Objective: Detection and analysis of Mongolian medicine Narenmandula the kernel full of adriamycin nephrosis rats kidney tissue expression of miRNA.
Methods: The biological information of the differentially expressed miRNA between the normal group, the model group and the Mongolian medicine Narenmandula group was studied by Affymetrix miRNA chip detection.
Results: The biological information of miRNA expression in kidney tissues of rats with doxorubicin nephropathy was analyzed by detection, which laid a foundation for further elucidating the multi-target regulatory role of Mongolian medicine Narenmandula in renal function protection and provided data.
The biological information of miRNA expression in renal tissues of doxorubicin rats was detected and analyzed using Affymetrix miRNA chip detection technology, which laid a foundation for further elucidating the multi-target regulation effect of the renal function protection and provided data of Mongolian medicine Narenmandula .
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| Overall design |
The rats were divided into three groups, namely normal group, model group and Mongolian medicine Narenmandula group ,containing 15 samples, the kidney tissue, through the tail vein injection adriamycin mold.
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| Contributor(s) |
Wang X |
| Citation(s) |
33299464 |
| |
| Submission date |
Dec 13, 2018 |
| Last update date |
Dec 15, 2020 |
| Contact name |
Xiulan Wang |
| E-mail(s) |
wangxl_1203@163.com
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| Organization name |
Inner Mongolia University For The Nationlities
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| Department |
Affiliated Hospital
|
| Street address |
HuoLinhe
|
| City |
Tongliao |
| State/province |
Inner Mongolia |
| ZIP/Postal code |
028000 |
| Country |
China |
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| Platforms (1) |
| GPL19117 |
[miRNA-4] Affymetrix Multispecies miRNA-4 Array |
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| Samples (15)
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| Relations |
| BioProject |
PRJNA509793 |
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