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Series GSE122420 Query DataSets for GSE122420
Status Public on Jul 10, 2019
Title Expression data from CSC and Non-CSC of three primary HCC samples
Organism Homo sapiens
Experiment type Expression profiling by array
Non-coding RNA profiling by array
Summary Hepatocellular carcinoma (HCC) represents the major subtype of liver cancer, characterized with a high rate of recurrence and heterogeneity. Liver cancer stem cells (CSCs) may account for a hierarchical organization of heterogeneous cancer cells. However, how liver CSCs sustain their self-renewal remains largely unknown.
We used microarrays to discover the long non-coding RNAs (lncRNAs) expression underlying cell stem cell (CSC) and non cell stem cell (non-CSC) and identified distinct lncRNAs during this process.
 
Overall design We sorted CD13+CD133+ and CD13-CD133- cells from three primary HCC patients as liver CSCs and non-CSCs, then hybridized on Aligent microarrays. We sought to identify distinct lncRNAs in liver CSCs.
 
Contributor(s) Wang Y
Citation(s) 31334575
Submission date Nov 12, 2018
Last update date Oct 09, 2019
Contact name Yanying Wang
E-mail(s) wyy0329@163.com
Organization name Institute of Biophysics, Chinese Academy of Sciences
Street address 15 Datun Road, Chaoyang District,Beijing 100101, China
City Beijing
ZIP/Postal code 100101
Country China
 
Platforms (1)
GPL20115 Agilent-067406 Human CBC lncRNA + mRNA microarray V4.0 (Probe name version)
Samples (3)
GSM3466358 HCC 1
GSM3466359 HCC 2
GSM3466360 HCC 3
Relations
BioProject PRJNA505166

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE122420_RAW.tar 49.7 Mb (http)(custom) TAR (of TXT)
Raw data provided as supplementary file
Processed data included within Sample table

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