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Series GSE122420 Query DataSets for GSE122420
Status Public on Jul 10, 2019
Title Expression data from CSC and Non-CSC of three primary HCC samples
Organism Homo sapiens
Experiment type Expression profiling by array
Non-coding RNA profiling by array
Summary Hepatocellular carcinoma (HCC) represents the major subtype of liver cancer, characterized with a high rate of recurrence and heterogeneity. Liver cancer stem cells (CSCs) may account for a hierarchical organization of heterogeneous cancer cells. However, how liver CSCs sustain their self-renewal remains largely unknown.
We used microarrays to discover the long non-coding RNAs (lncRNAs) expression underlying cell stem cell (CSC) and non cell stem cell (non-CSC) and identified distinct lncRNAs during this process.
Overall design We sorted CD13+CD133+ and CD13-CD133- cells from three primary HCC patients as liver CSCs and non-CSCs, then hybridized on Aligent microarrays. We sought to identify distinct lncRNAs in liver CSCs.
Contributor(s) Wang Y
Citation(s) 31334575
Submission date Nov 12, 2018
Last update date Oct 09, 2019
Contact name Yanying Wang
Organization name Institute of Biophysics, Chinese Academy of Sciences
Street address 15 Datun Road, Chaoyang District,Beijing 100101, China
City Beijing
ZIP/Postal code 100101
Country China
Platforms (1)
GPL20115 Agilent-067406 Human CBC lncRNA + mRNA microarray V4.0 (Probe name version)
Samples (3)
GSM3466358 HCC 1
GSM3466359 HCC 2
GSM3466360 HCC 3
BioProject PRJNA505166

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Supplementary file Size Download File type/resource
GSE122420_RAW.tar 49.7 Mb (http)(custom) TAR (of TXT)
Raw data provided as supplementary file
Processed data included within Sample table

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