|
| Status |
Public on Nov 07, 2018 |
| Title |
H3K27me3 and CTCF ChIP-seq in reciprocal wild-type and SmcHD1 MommeD1mut MEF cell lines |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
In this study we investigate the role of the non-canonical SMC family protein, SmcHD1in the X inactivation.
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| Overall design |
Set of allele-specific ChIP-seq experiments on female clonal inter-specific (M.m.domesticus FVB x M.m.Castaneus) MEF cell lines: wild-type MEFs, SmcHD1 MomeD1 mut MEFs (SmcHD1 null) and SmcHD1 CRISPR KO MEFs (derived from wild-type MEFs after establishemnt of X inactivation). Each ChIP library was accompanied with respective input library and each experiment was done in biological replicates (2-4).
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| Contributor(s) |
Gdula MR, Nesterova TB, Pintacuda G, Godwin J, McClellan M, Kriaucionis S, Krueger F, Reik W, Zhan Y, Ozadam H, Dekker J, Green CM, Moralli D, Heard E, Brockdorff N |
| Citation(s) |
30604745 |
| |
| Submission date |
Oct 31, 2018 |
| Last update date |
Jan 15, 2019 |
| Contact name |
Michal R. Gdula |
| E-mail(s) |
michal.gdula@bioch.ox.ac.uk
|
| Organization name |
Oxford University
|
| Street address |
South Parks Road
|
| City |
Oxford |
| ZIP/Postal code |
OX1 3RF |
| Country |
United Kingdom |
| |
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| Platforms (1) |
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| Samples (24)
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| This SubSeries is part of SuperSeries: |
| GSE115984 |
The non-canonical SMC protein SmcHD1 antagonises TAD formation on the inactive X chromosome |
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| Relations |
| BioProject |
PRJNA503181 |
| SRA |
SRP167338 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE122019_CTCF_mut_IP_Cast_merged_MEF_reciprocal030718.bedGraph.bw |
301.9 Mb |
(ftp)(http) |
BW |
| GSE122019_CTCF_mut_IP_FVB_merged_MEF_reciprocal030718.bedGraph.bw |
393.6 Mb |
(ftp)(http) |
BW |
| GSE122019_CTCF_mut_IP_merged_MEF_reciprocal030718.bedGraph.bw |
530.0 Mb |
(ftp)(http) |
BW |
| GSE122019_CTCF_mut_input_Cast_merged_MEF_reciprocal030718.bedGraph.bw |
289.0 Mb |
(ftp)(http) |
BW |
| GSE122019_CTCF_mut_input_FVB_merged_MEF_reciprocal030718.bedGraph.bw |
367.1 Mb |
(ftp)(http) |
BW |
| GSE122019_CTCF_mut_input_merged_MEF_reciprocal030718.bedGraph.bw |
486.9 Mb |
(ftp)(http) |
BW |
| GSE122019_CTCF_wt_IP_Cast_merged_MEF_reciprocal030718.bedGraph.bw |
327.9 Mb |
(ftp)(http) |
BW |
| GSE122019_CTCF_wt_IP_FVB_merged_MEF_reciprocal030718.bedGraph.bw |
405.3 Mb |
(ftp)(http) |
BW |
| GSE122019_CTCF_wt_IP_merged_MEF_reciprocal030718.bedGraph.bw |
538.4 Mb |
(ftp)(http) |
BW |
| GSE122019_CTCF_wt_input_Cast_merged_MEF_reciprocal030718.bedGraph.bw |
302.6 Mb |
(ftp)(http) |
BW |
| GSE122019_CTCF_wt_input_FVB_merged_MEF_reciprocal030718.bedGraph.bw |
365.5 Mb |
(ftp)(http) |
BW |
| GSE122019_CTCF_wt_input_merged_MEF_reciprocal030718.bedGraph.bw |
487.3 Mb |
(ftp)(http) |
BW |
| GSE122019_mut_IPlog_merged_MEF_reciprocal110618.bedGraph.bw |
62.4 Mb |
(ftp)(http) |
BW |
| GSE122019_mut_IPlog_merged_MEF_reciprocal110618_Cast.bedGraph.bw |
41.4 Mb |
(ftp)(http) |
BW |
| GSE122019_mut_IPlog_merged_MEF_reciprocal110618_FVB.bedGraph.bw |
55.4 Mb |
(ftp)(http) |
BW |
| GSE122019_wt_IPlog_merged_MEF_reciprocal110618.bedGraph.bw |
62.4 Mb |
(ftp)(http) |
BW |
| GSE122019_wt_IPlog_merged_MEF_reciprocal110618_Cast.bedGraph.bw |
45.4 Mb |
(ftp)(http) |
BW |
| GSE122019_wt_IPlog_merged_MEF_reciprocal110618_FVB.bedGraph.bw |
55.9 Mb |
(ftp)(http) |
BW |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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