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Series GSE118482 Query DataSets for GSE118482
Status Public on Aug 01, 2020
Title Effect of 6-azasteroids on Mycobacterium tuberculosis wild type and 6-azasteroid resistant mutants
Organism Mycobacterium tuberculosis
Experiment type Expression profiling by high throughput sequencing
Summary Transcriptional profiling of Mycobacterium tuberculosis CDC1551 and 6-azasteroid resistant mutants ASR1 and ASR2 with treatment of 6-azasteroids, 4a and 6a, for 6 hours.
Overall design Three different strains, wild type CDC1551 and two clones resistant to compound 6a, ASR1 and ASR2, were grown to OD~0.6 and treated with 30 μM of 4a or 6a or vehicle control for 6h. Total RNA was extracted and processed for RNAseq.
Contributor(s) Yang X, Sampson NS
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Submission date Aug 13, 2018
Last update date Aug 01, 2020
Contact name Xinxin Yang
Organization name Stony Brook University
Department Chemistry
Lab Nicole Sampson
Street address 100 Nicolls Road
City Stony Brook
State/province New York
ZIP/Postal code 11794
Country USA
Platforms (1)
GPL22688 Illumina NextSeq 500 (Mycobacterium tuberculosis)
Samples (27)
GSM3330731 CDC1551_control_rep1
GSM3330732 CDC1551_control_rep2
GSM3330733 CDC1551_control_rep3
BioProject PRJNA485761
SRA SRP157724

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Supplementary file Size Download File type/resource
GSE118482_CDC_ASR1_ASR2_azasteroids.csv.gz 603.5 Kb (ftp)(http) CSV
GSE118482_SBU_Sampson_individual_rpkm.txt.gz 670.5 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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