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Series GSE118189 Query DataSets for GSE118189
Status Public on Sep 05, 2018
Title ATAC-seq data
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary The immune system depends on a balanced interplay among a variety of specialized cell types transitioning between resting and stimulated states. While epigenome mapping efforts have focused on resting ex vivo immune cells, efforts to characterize stimulation-induced chromatin changes of diverse cell types has been limited. Thus, we collected ATAC-seq and RNA-seq data from immune cell types under resting and stimulated conditions from blood of healthy individuals, and cell types from fetal thymus samples.
Overall design 175 ATAC-seq samples of 25 blood cell types from healthy donors.
Contributor(s) Calderon D, Nguyen ML, Mezger A
Citation Diego Calderon, Michelle L.T. Nguyen, Anja Mezger, Arwa Kathiria, Vinh Nguyen, Ninnia Lescano, Beijing Wu, John Trombetta, Jessica V. Ribado, David A. Knowles, Ziyue Gao, Audrey V. Parent, Trevor D. Burt, Mark S. Anderson, Lindsey A. Criswell, William J. Greenleaf, Alexander Marson, and Jonathan K. Pritchard. Landscape of stimulation-responsive chromatin across diverse human immune cells. bioRxiv 409722; doi:10.1101/409722
Submission date Aug 06, 2018
Last update date Mar 21, 2019
Contact name Diego Calderon
Organization name University of Washington
Street address 3720 15th Ave NE
City Seattle
ZIP/Postal code 98105
Country USA
Platforms (2)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (175)
GSM3320229 1001-Bulk_B-U
GSM3320230 1001-Bulk_B-S
GSM3320231 1001-Mem_B-U
BioProject PRJNA484801
SRA SRP156496

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Supplementary file Size Download File type/resource
GSE118189_ATAC_counts.txt.gz 111.3 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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