|
| Status |
Public on Aug 04, 2019 |
| Title |
Inverse data-driven modelling and multiomics analysis reveals PHGDH as a metabolic signature of M2 macrophages |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
RNAseq data from C57BL/6 bone marrow-derived macrophages that were stimulated with IL-4 in the presence or absence of the PHGDH inhibitor CBR-5884.
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| |
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| Overall design |
BMDM were pre-treated with either 30 µM CBR-5884 (AxonMedchem) or solvent. Thereafter, 10 ng/ml IL-4 (Peprotech) was added and cells were harvested 24h later for RNA isolation.
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| |
|
| Contributor(s) |
Wilson JL, Linke M, Weichhart T |
| Citation(s) |
32023468 |
| |
| Submission date |
Aug 03, 2018 |
| Last update date |
Feb 18, 2020 |
| Contact name |
Thomas Weichhart |
| E-mail(s) |
thomas.weichhart@meduniwien.ac.at
|
| Organization name |
Medical University of Vienna
|
| Department |
Center for Pathobiochemistry and Genetics
|
| Street address |
Waehringerstraße 10
|
| City |
Vienna |
| ZIP/Postal code |
1090 |
| Country |
Austria |
| |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (5)
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|
| Relations |
| BioProject |
PRJNA484506 |
| SRA |
SRP156337 |
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