|
| Status |
Public on Jul 01, 2021 |
| Title |
Gefitinib treatment in human EGFR-driven-Gefitinib resistant tumoral cell line |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
In order to analyze the molecular effect of the combination of Notch inhibitors and EGFR inhibitors on resistance to TKI,
we performed RNA-seq gene expression profiling of PC9 resistant to Gefitinib cells treated with different combinations.
|
| |
|
| Overall design |
Cells were treated with each drug alone (DBZ for Notch inhibition or Gefitinib for EGFR inhibition) or a combination of both drugs.
|
| |
|
| Contributor(s) |
Maraver A, Colinge J, Bousquet E, Bernardo S |
| Citation missing |
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| |
| Submission date |
Jul 30, 2018 |
| Last update date |
Jul 01, 2021 |
| Contact name |
Jacques Colinge |
| E-mail(s) |
jacques.colinge@inserm.fr
|
| Organization name |
Inserm
|
| Lab |
IRCM
|
| Street address |
208, avenue des Apothicaires
|
| City |
Montpellier |
| ZIP/Postal code |
34000 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA483409 |
| SRA |
SRP155717 |
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