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Series GSE11710 Query DataSets for GSE11710
Status Public on Oct 29, 2008
Title TGF-beta-induced gene expression data and Smad2/3 binding sites of HaCaT keratinocytes
Organism Homo sapiens
Experiment type Expression profiling by array
Genome binding/occupancy profiling by genome tiling array
Summary Smad2/3 are transcription factors that engage in TGF-beta-induced transcription. Here we analyzed the effect of identified Smad2/3 binding sites to transcription. We used expression microarrays to compare the Smad2/3 binding sites identified by ChIP-chip to TGF-beta-induced gene expressions. Keywords: time course
We also examined the effect of either ETS1/TFAP2A/SMAD2/SMAD3 siRNAs on TGF-beta-induced gene expression change.
Overall design HaCaT cells were treated with TGF-beta3 for Smad2/3 ChIP-chip or RNA extraction and hybridization on Affymetrix microarrays.
Contributor(s) Koinuma D, Tsutsumi S
Citation(s) 18955504
Submission date Jun 09, 2008
Last update date Mar 25, 2019
Contact name Daizo Koinuma
Organization name University of Tokyo
Department Molecular Pathology
Street address Hongo 7-3-1, Bunkyo-ku
City Tokyo
ZIP/Postal code 113-0033
Country Japan
Platforms (2)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
GPL7026 Human Promoter Array 1.0R - NCBI build_35
Samples (20)
GSM297456 HaCaT_0h
GSM297457 HaCaT_1.5h
GSM297458 HaCaT_6h
BioProject PRJNA106007

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE11710_RAW.tar 595.1 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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