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Series GSE115414 Query DataSets for GSE115414
Status Public on Nov 12, 2019
Title Discovery of lncRNA biomarkers of prostate cancer
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary In the last decade, new high-throughput sequencing techniques have revealed the complexity of the human transcriptome, allowing the characterization of long non-coding (lnc)RNAs. Since their expression has been reported as very specific to tissue, developmental stage and pathological variations, some lncRNAs have been proposed as biomarkers for diagnosis as well as prognosis of tumors. In this project, we aim to build an exhaustive catalogue of long non-coding RNAs and isolate those which allow detection and risk assessement of prostate cancer. For this purpose we performed a high throughput total stranded RNA-sequencing of 24 samples (8 normal and 16 tumor tissues).
Overall design Total RNA was extracted from biopsy specimens, checked for the quality and than converted into cDNA for total stranded RNA-sequencing.
Contributor(s) Pinskaya M, Gabriel M, Morillon A
Citation(s) 31732695
Submission date Jun 06, 2018
Last update date Nov 18, 2019
Contact name Marina Pinskaya
Phone 0156246598
Organization name Institut Curie
Lab Non Coding RNA, Epigenetic and Genome Fluidity
Street address 26 rue d'Ulm
City Paris
ZIP/Postal code 75248
Country France
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (24)
GSM3177829 Prostate: HMN_PC_102
GSM3177830 Prostate: HMN_PC_228
GSM3177831 Prostate: HMN_PC_089
BioProject PRJNA474912
SRA SRP149919

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE115414_RAW.tar 23.8 Mb (http)(custom) TAR (of TSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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