|
| Status |
Public on Jun 01, 2020 |
| Title |
WT and aP2-Cre Adipocyte Bmal1 KO 24hr Time Course, Liver Tissue RNA-seq |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Liver metabolism in mice lacking Bmal1 in adipocytes. Comparison between WT and KO revealed no differentially expressed genes at ZT12 and ZT16, and only revealed one gene at ZT8 and ZT20. In contrast many genes were differential at ZT0 and ZT4. With ZT4 having substantially more than ZT0.
|
| |
|
| Overall design |
Time-series liver mRNA profiles of 4- to 6-month-old male wild type (WT) and Bmal1 knockout (KO) mice were generated by sequencing, four mice per genotype per timepoint, using Illumina HiSeq 2000.
|
| |
|
| Contributor(s) |
Yang G, Paschos GK, Grant GR, FitzGerald G, Chen L |
| Citation(s) |
34724846 |
| |
| Submission date |
Jun 04, 2018 |
| Last update date |
Apr 08, 2022 |
| Contact name |
Gregory Robert Grant |
| E-mail(s) |
ggrant@upenn.edu
|
| Phone |
215-573-3736
|
| Organization name |
University of Pennsylvania
|
| Department |
Genetics
|
| Lab |
ITMAT Bioinformatics
|
| Street address |
3400 Civic Center Blvd.
|
| City |
Philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (48)
|
|
| Relations |
| BioProject |
PRJNA474430 |
| SRA |
SRP149661 |
Less...
More...