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Series GSE115264 Query DataSets for GSE115264
Status Public on Jun 01, 2020
Title WT and aP2-Cre Adipocyte Bmal1 KO 24hr Time Course, Liver Tissue RNA-seq
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Liver metabolism in mice lacking Bmal1 in adipocytes. Comparison between WT and KO revealed no differentially expressed genes at ZT12 and ZT16, and only revealed one gene at ZT8 and ZT20. In contrast many genes were differential at ZT0 and ZT4. With ZT4 having substantially more than ZT0.
Overall design Time-series liver mRNA profiles of 4- to 6-month-old male wild type (WT) and Bmal1 knockout (KO) mice were generated by sequencing, four mice per genotype per timepoint, using Illumina HiSeq 2000.
Contributor(s) Yang G, Paschos GK, Grant GR, FitzGerald G, Chen L
Citation(s) 34724846
Submission date Jun 04, 2018
Last update date Apr 08, 2022
Contact name Gregory Robert Grant
Phone 215-573-3736
Organization name University of Pennsylvania
Department Genetics
Lab ITMAT Bioinformatics
Street address 3400 Civic Center Blvd.
City Philadelphia
State/province PA
ZIP/Postal code 19104
Country USA
Platforms (1)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (48)
GSM3172819 Sample_13015GP35
GSM3172820 Sample_13015GP18
GSM3172821 Sample_13015GP15
BioProject PRJNA474430
SRA SRP149661

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Supplementary file Size Download File type/resource
GSE115264_FINAL_master_list_of_genes_counts_MIN.sense.8_paschos_rnaseq1.highExp.txt.gz 1.6 Mb (ftp)(http) TXT
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