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Series GSE115098 Query DataSets for GSE115098
Status Public on Nov 16, 2018
Title Kidney compartment specific eQTL studies highlight causal genes and pathways for renal disease development
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Expression quantitative trait loci (eQTL) analyses were conducted separately on the glomerular and tubular portions of healthy human kidney samples obtained from subjects of European descent.
 
Overall design We aimed to define genotype driven gene expression changes in the glomerular and tubular compartments of human kidneys, identifying genetic variants (eVariants) that influence the expression of genes (eGenes). Later, we integrated this information with genotype and phenotype association studies (GWAS) to identify genes for which expression in the kidney shows differences in patients with GWAS variants.
 
Contributor(s) Qiu C, Susztak K
Citation(s) 30275566, 31167971, 31451708, 34426578
Submission date May 30, 2018
Last update date Sep 29, 2021
Contact name Chengxiang Qiu
E-mail(s) cxqiu@uw.edu
Organization name University of Washington
Department Genome Sciences
Lab Jay Shendure
Street address William H. Foege Hall, 3720 15th Ave NE
City Seattle
State/province WA
ZIP/Postal code 98195
Country USA
 
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (20)
GSM3165120 kidney sample 1
GSM3165121 kidney sample 2
GSM3165122 kidney sample 3
Relations
BioProject PRJNA473790
SRA SRP149347

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE115098_RAW.tar 6.4 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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