|
| Status |
Public on May 08, 2018 |
| Title |
The impact on reprogramming of Msx2 |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We report that we make the high-profiling for transcriptome to detect the impact on reprogramming of transcription factor Msx2 at different time points during reprogramming. Based on the technology of overexpression and Knock down for Msx2, we can observe the changes of transcriptomes in contrast with control group. We get the connections between Msx2 and BMP signaling, and other meaningful results, but we should make further validation.
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| |
|
| Overall design |
Examination of the impact on reprogramming of Msx2
|
| |
|
| Contributor(s) |
Lin L, Zheng H |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
May 07, 2018 |
| Last update date |
Jan 27, 2019 |
| Contact name |
lilong Lin |
| E-mail(s) |
lin_lilong@gibh.ac.cn
|
| Organization name |
Guangzhou Institutes of Biomedicine and Health，Chinese Academy of Sciences
|
| Street address |
190 Kai Yuan Avenue, Science Park, Guangzhou, China
|
| City |
Guangzhou |
| ZIP/Postal code |
510530 |
| Country |
China |
| |
|
| Platforms (1) |
|
| Samples (8)
|
| GSM3133234 |
Mouse embryonic fibroblast |
| GSM3133235 |
Sox2/Klf4/Oct4/cMyc and Flag infected MEF at day4 |
| GSM3133236 |
Sox2/Klf4/Oct4/cMyc and Flag infected MEF at day8 |
| GSM3133237 |
Sox2/Klf4/Oct4/cMyc and Msx2 infected MEF at day4 |
| GSM3133238 |
Sox2/Klf4/Oct4/cMyc and Msx2 infected MEF at day8 |
| GSM3133239 |
Sox2/Klf4/Oct4/cMyc and shMsx2 infected MEF at day4 |
| GSM3133240 |
Sox2/Klf4/Oct4/cMyc and shMsx2 infected MEF at day8 |
| GSM3133241 |
Mouse embryonic stem cell |
|
| Relations |
| BioProject |
PRJNA464364 |
| SRA |
SRP144751 |
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