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Status |
Public on May 08, 2018 |
Title |
Genomewide mapping of Trim33 binding in Th17 cells |
Organism |
Mus musculus |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
We report the genome-wide binding of Trim33 in Th17 cells. We found that more than 90% of Trim33 binding regions was located in non-conding sequence, and therefore reflect the role of Trim33 as a trancriptional co-factor. Trim33 was found to accumulate on cis-regulatory regions of genes that regulate the function of Th17 cells such as Il17a, Ccr6 and Il10. This study provides a basis for the comprehensive understanding of Trim33-mediated regulation of Th17 cells.
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Overall design |
Examination of Trim33 binding in Th17 cells.
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Contributor(s) |
Tanaka S, Jiang Y |
Citation(s) |
29930104 |
Submission date |
May 07, 2018 |
Last update date |
Mar 19, 2019 |
Contact name |
SHINYA TANAKA |
Organization name |
Kyushu University
|
Street address |
3-1-1, maidashi, Higashi-ku
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City |
Fukuoka |
ZIP/Postal code |
812-8582 |
Country |
Japan |
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Platforms (1) |
GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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Samples (4)
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Relations |
BioProject |
PRJNA464365 |
SRA |
SRP144755 |