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Series GSE114119 Query DataSets for GSE114119
Status Public on May 08, 2018
Title Genomewide mapping of Trim33 binding in Th17 cells
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We report the genome-wide binding of Trim33 in Th17 cells. We found that more than 90% of Trim33 binding regions was located in non-conding sequence, and therefore reflect the role of Trim33 as a trancriptional co-factor. Trim33 was found to accumulate on cis-regulatory regions of genes that regulate the function of Th17 cells such as Il17a, Ccr6 and Il10. This study provides a basis for the comprehensive understanding of Trim33-mediated regulation of Th17 cells.
 
Overall design Examination of Trim33 binding in Th17 cells.
 
Contributor(s) Tanaka S, Jiang Y
Citation(s) 29930104
Submission date May 07, 2018
Last update date Mar 19, 2019
Contact name SHINYA TANAKA
Organization name Kyushu University
Street address 3-1-1, maidashi, Higashi-ku
City Fukuoka
ZIP/Postal code 812-8582
Country Japan
 
Platforms (1)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (4)
GSM3133230 Trim33_ChIPSeq_1
GSM3133231 Trim33_ChIPSeq_2
GSM3133232 input DNA_1
Relations
BioProject PRJNA464365
SRA SRP144755

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE114119_Th17_Trim33replicateMerged_peak.bed.gz 633.0 Kb (ftp)(http) BED
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Raw data are available in SRA
Processed data are available on Series record

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