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Series GSE1133 Query DataSets for GSE1133
Status Public on Mar 19, 2004
Title tissue-specific pattern of mRNA expression
Organisms Homo sapiens; Mus musculus
Experiment type Expression profiling by array
Summary The tissue-specific pattern of mRNA expression can indicate important clues about gene function. High-density oligonucleotide arrays offer the opportunity to examine patterns of gene expression on a genome scale. Toward this end, we have designed custom arrays that interrogate the expression of the vast majority of protein-encoding human and mouse genes and have used them to profile a panel of 79 human and 61 mouse tissues. The resulting data set provides the expression patterns for thousands of predicted genes, as well as known and poorly characterized genes, from mice and humans. We have explored this data set for global trends in gene expression, evaluated commonly used lines of evidence in gene prediction methodologies, and investigated patterns indicative of chromosomal organization of transcription. We describe hundreds of regions of correlated transcription and show that some are subject to both tissue and parental allele-specific expression, suggesting a link between spatial expression and imprinting.
Keywords: different tissues
 
Overall design baseline gene expression was taken from various human and mouse tissues
 
Contributor(s) Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, Block D, Zhang J, Soden R, Hayakawa M, Kreiman G, Cooke MP, Walker JR, Hogenesch JB
Citation(s) 15075390
Submission date Mar 19, 2004
Last update date Aug 10, 2018
Contact name John R Walker
E-mail jwalker@gnf.org
Phone 858-812-1636
Organization name Genomics Institute of the Novartis Research Foundation
Lab Genetics Core
Street address 10675 John Jay Hopkins
City San Diego
State/province CA
ZIP/Postal code 92121
Country USA
 
Platforms (3)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
GPL1073 GNF1M
GPL1074 GNF1H
Samples (438)
GSM18584 MGJZ030212072Asubstantianigra
GSM18585 MGJZ030212072Bsubstantianigra
GSM18586 MGMH030212058Aspinalcordupper
Relations
BioProject PRJNA87249

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE1133_RAW.tar 1.7 Gb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file

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