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| Status |
Public on Dec 29, 2019 |
| Title |
Expression data of miRNAs from splenic leukocytes of dogs infected with L. infantum |
| Platform organism |
synthetic construct |
| Sample organism |
Canis lupus familiaris |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
The disease visceral leishmaniasis (VL), caused by Leishmania (L.) infantum, its a serious public health problem in Brazil. Studies with miRNAs showed their regulation in the immune response, due to cell immune suppression to be determinant at disease progression, identify them is important for the mechanism of change in immune response. We suggest then, that miRNAs regulation at immune response of dogs with VL.
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| Overall design |
Fourteen dogs were used to form two groups for the study: 5 healthy dogs in Control group and 9 dogs naturally infected with L. infantum in Infected group.
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| Contributor(s) |
Melo LM, Bragato JP, Venturin GL, Rebech GT, de Araújo Júnior EC, Garcia LE, Eugênio FR, dos Santos PS, Lopes FL, Lima VM |
| Citation(s) |
31825987 |
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| Submission date |
Mar 28, 2018 |
| Last update date |
Dec 29, 2019 |
| Contact name |
Larissa Martins Melo |
| E-mail(s) |
lala_mmelo@yahoo.com.br
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| Organization name |
UNESP
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| Street address |
Clovis Pestana st, 793
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| City |
Araçatuba |
| ZIP/Postal code |
16050-680 |
| Country |
Brazil |
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| Platforms (1) |
| GPL19117 |
[miRNA-4] Affymetrix Multispecies miRNA-4 Array |
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| Samples (14)
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| Relations |
| BioProject |
PRJNA447431 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE112459_RAW.tar |
11.3 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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