|
| Status |
Public on Mar 14, 2018 |
| Title |
Droplet based single cell RNA sequencing profiles of a murine model of type-1 diabetes |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Diabetic kidney disease remains the leading cause of end-stage renal disease, affecting ~30% of patients with long-standing type 1 and type 2 diabetes, and is characterized by proteinuria and gradual loss of kidney function. There is intense interest in understanding the responses of the many cell types present in the kidney to the diabetic milleu. In this study, we present single cell transcriptomes of renal cortex samples of wild-type and diabetic (C57BL/6-Ins2Akita/J) mice using Drop-Seq.
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| Overall design |
Renal cortex samples from wild type and diabetic Akita mice (n=2 per group) underwent dissociation and Drop-seq.
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| Contributor(s) |
Maxwell S, Ziemann M, Sourris KC, Al-Hasani K, El-Osta A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Mar 13, 2018 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Mark D Ziemann |
| E-mail(s) |
mark.ziemann@gmail.com
|
| Organization name |
Burnet Institute
|
| Department |
Bioinformatics Working Group
|
| Street address |
85 Commercial Rd
|
| City |
Melbourne |
| State/province |
VIC |
| ZIP/Postal code |
3004 |
| Country |
Australia |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA438067 |
| SRA |
SRP135249 |
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