|
| Status |
Public on Feb 11, 2019 |
| Title |
Exosomal miRNA sequencing from KPCY mice |
| Organism |
Mus musculus |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
We identified exosomal miRNA biomarkers for pancreatic cancer diagnostics by isolating exosomes using a recently developed magnetic nanopore isolation technology and small RNA sequencing.
|
| |
|
| Overall design |
Small RNA sequencing from three different groups of mice (control, PanIN, PDAC) in 2-6 replicates.
|
| |
|
| Contributor(s) |
Ko J, Bhagwat N, Black T, Yee SD, Na Y, Fisher SA, Kim J, Carpenter EL, Stanger B, Issadore D |
| Citation(s) |
29735554 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R21 CA182336 |
A micro Hall chip for circulating microvesicle based cancer monitoring |
UNIVERSITY OF PENNSYLVANIA |
David Aaron Issadore |
| R01 CA169123 |
Immunobiology and immunotherapy of pancreatic cancer |
UNIVERSITY OF PENNSYLVANIA |
BEN Z STANGER |
| F32 CA196120 |
A cell-based liquid biopsy approach for early pancreatic cancer detection |
UNIVERSITY OF PENNSYLVANIA |
Neha Bhagwat |
| R01 CA207643 |
Real-time monitoring of circulating pancreatic tumor cells and clusters |
UNIVERSITY OF PENNSYLVANIA |
Erica Carpenter |
|
| |
| Submission date |
Mar 13, 2018 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Junhyong Kim |
| Organization name |
University of Pennsylvania
|
| Department |
Biology
|
| Lab |
Junhyong Kim
|
| Street address |
433 S University Avenue
|
| City |
Philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (13)
|
|
| Relations |
| BioProject |
PRJNA438065 |
| SRA |
SRP135248 |
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