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Series GSE111280 Query DataSets for GSE111280
Status Public on May 20, 2019
Title Whole transcriptomic analysis of zebrafish embryos of dyrk1aakrb1, dyrk1aa knock out mutant and Wild Type (WT) (+/+) in the background of Tg(kdrl:egfp)
Organism Danio rerio
Experiment type Expression profiling by high throughput sequencing
Summary Purpose: The goals of this experiments are to analyze the transcriptomic change in dyrk1aakrb1 mutants compared with WT embryos by mRNA-seq technique. Methods: Whole mRNA profiles of 48 hpf WT(+/+) and dyrk1aakrb1 mutants zebrafish embryos were generated by mRNA-seq techinque, in duplicate, using HiSeq 2500 (Illumina, Inc., USA). Results: This analysis identified 222 transcripts as differentially regulated genes (DEG), of which 101 were up-regulated and 121 were down-regulated in dyrk1aakrb1 mutant (more than 2 fold and less than 0.5 fold respectively,; p value< 0.05).
Overall design Whole transcriptomic analysis of zebrafish embryos of dyrk1aakrb1, dyrk1aa knock out mutant and WT (+/+) in the background of Tg(kdrl:egfp) at 48 hpf.
Contributor(s) Cho H, Lee J, Kim JH, Kim SY
Citation(s) 31043432
Submission date Feb 28, 2018
Last update date Jun 20, 2019
Contact name Jong Hwan Kim
Phone 0821093299557
Organization name Korea Research Institute of Bioscience and Biotechnology
Department Genome structure research center
Street address 125 Gwahak-ro, Yuseong-gu
City Daejeon
ZIP/Postal code ASI|KR|KS015|DAEJEON
Country South Korea
Platforms (1)
GPL18413 Illumina HiSeq 2500 (Danio rerio)
Samples (4)
GSM3027772 AB (WT, +/+) -1
GSM3027773 AB (WT, +/+) -2
GSM3027774 dyrk1aakrb1 (mutant, -/-) -1
BioProject PRJNA436393
SRA SRP133688

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Supplementary file Size Download File type/resource
GSE111280_cpm_normalized_log2.txt.gz 552.1 Kb (ftp)(http) TXT
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Processed data are available on Series record

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