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Series GSE110188 Query DataSets for GSE110188
Status Public on Feb 07, 2018
Title Neuro-glial crosstalk regulates microglia activation and control of viral encephalitis
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary In this study it was possible to compare the behaviour of different myeloid cell populations upon VSV infection.
Overall design Non-activated microglia (Ly6G-CD45lowCD11b+Tomato+ cells) and activated microglia (Ly6G-CD45highCD11b+Tomato+ cells) from olfactory bulb and infiltrating monocytes (Ly6G-CD45highCD11bhigh-Tomato-) were FACS-sorted from Cx3cr1CreER:R26-Tomato mice in which all resident macrophages express the endogenous tomato signal while peripheral immune cells do not. The mRNA from the different populations was extracted and sequenced on Illumina HiSeq RNA-Seq. Three replicates per condition were used. As a control (reference samples) were used three replicates from non-activated microglia from non-infected mice (CCE9701-CCE9703). All the other samples are coming from VSV-infected mice.
Contributor(s) Chhatbar C, Jordao M, Prinz M, Kalinke U
Citation(s) 30282022
Submission date Feb 06, 2018
Last update date Apr 06, 2020
Contact name Marta Joana Costa Jordão
Organization name Uniklinikum Freiburg
Department Neuropathology
Street address Breisacher strasse 64
City Freiburg
ZIP/Postal code 79106
Country Germany
Platforms (1)
GPL15103 Illumina HiSeq 1000 (Mus musculus)
Samples (12)
GSM2981892 Sample_CCE9701
GSM2981893 Sample_CCE9702
GSM2981894 Sample_CCE9703
BioProject PRJNA433097
SRA SRP132259

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE110188_RAW.tar 2.0 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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