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Series GSE109816 Query DataSets for GSE109816
Status Public on Oct 21, 2019
Title Dissecting cell composition and cell-cell interaction network of normal human heart tissue by single-cell sequencing
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We studied the cell compositon of normal human heart by single-cell sequencing. Distint subgroups of cardiac muscle, fibroblast cell and endothelial cell were detected. We drawed a cell-cell interaction network using specific expressed ligands and receptors of cells. And we also observed the change of interaction and cell transformation with age.
 
Overall design Extract cells from left ateria and ventricle of normal heart and conduct single-cell sequencing of 9994 cells.
 
Contributor(s) Wang L, Yu P, Li Z, Ren Z
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Jan 29, 2018
Last update date Oct 21, 2019
Contact name Li Wang
Organization name NIH
Street address 111 T.W. Alexander Dr
City Durham
ZIP/Postal code 27709
Country USA
 
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (12)
GSM2970358 N2_LV
GSM2970359 N6_LA
GSM2970360 N5_LV
Relations
BioProject PRJNA432074
SRA SRP131694

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE109816_metadata_barcodes_9994cells.txt.gz 689.6 Kb (ftp)(http) TXT
GSE109816_normal_heart_cell_info.txt.gz 571.1 Kb (ftp)(http) TXT
GSE109816_normal_heart_umi_matrix.csv.gz 33.1 Mb (ftp)(http) CSV
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Raw data are available in SRA
Processed data are available on Series record

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