|
| Status |
Public on Aug 30, 2018 |
| Title |
Paternal exposure to Arctic contaminants alters the sperm epigenome and induces negative pregnancy outcomes transgenerationally |
| Organism |
Rattus norvegicus |
| Experiment type |
Methylation profiling by high throughput sequencing
|
| Summary |
Paternal exposure to environmentally-relevant Arctic contaminants induces adverse health outcomes and alters the sperm methylome over three generations.
|
| |
|
| Overall design |
Genome-wide methylation profiles of rat epididymal sperm across F1, F2 and F3 generations spermatozoa profiles (6 organochlorines exposed and 6 controls per generation)
|
| |
|
| Contributor(s) |
Bailey JL |
| Citation(s) |
29750268, 34968297 |
| |
| Submission date |
Jan 10, 2018 |
| Last update date |
Jan 10, 2022 |
| Contact name |
Delphine Bernard |
| Organization name |
UMR1078 - Université de Bretagne Occidentale
|
| Department |
Faculté de Médecine
|
| Street address |
22 avenue Camille Desmoulins
|
| City |
BREST |
| ZIP/Postal code |
29200 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL14844 |
Illumina HiSeq 2000 (Rattus norvegicus) |
|
| Samples (48)
|
|
| Relations |
| BioProject |
PRJNA429491 |
| SRA |
SRP128759 |
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