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| Status |
Public on Mar 01, 2018 |
| Title |
Tumor evolution in the context of castration resistance in prostate cancer |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by array
|
| Summary |
Clinical resection specimens of prostate tissue (radical prostatectomy and TUR-P) over the course of hormone deprivation therapy were flow sorted according to their DNA content (Ploidy) and subjected to aCGH analysis to identify possiple chromosomal abberations which could confer castration resistance.
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| Overall design |
7 Patients where multiple timepoints were avaiable were first flow sorted according to DNA content and then hypridized on Agilent aCGH arrays.
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| Contributor(s) |
Federer-Gsponer JR, Quintavalle C, Müller DC, Dietsche T, Perrina V, Lorber T, Juskevicius D, Lenkiewicz E, Zellweger T, Gasser T, Barrett MT, Rentsch CA, Bubendorf L, Ruiz C |
| Citation(s) |
29484655 |
| |
| Submission date |
Dec 18, 2017 |
| Last update date |
Jun 08, 2018 |
| Contact name |
Joël Roman Federer-Gsponer |
| Organization name |
University Hospital Basel
|
| Department |
Department of Pathology
|
| Street address |
Tangentenweg 34
|
| City |
Basel |
| ZIP/Postal code |
4058 |
| Country |
Switzerland |
| |
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| Platforms (3) |
| GPL4091 |
Agilent-014693 Human Genome CGH Microarray 244A (Feature number version) |
| GPL9777 |
Agilent-021850 SurePrint G3 Human CGH Microarray (Feature Number version) |
| GPL21857 |
Agilent-022060 SurePrint G3 Human CGH Microarray 4x180K (Feature Number version, hg19/GRCh37) |
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| Samples (28)
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| Relations |
| BioProject |
PRJNA422863 |
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