NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE107910 Query DataSets for GSE107910
Status Public on Jun 05, 2018
Title Single-cell RNA sequencing resolves cellular heterogeneity throughout embryonic development of the thymus
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary This dataset consists of single-cell RNA-seq (Drop-seq) data from eight days of mouse thymus development. Samples span from embryonic day 12.5, when the thymus coalesces, until birth. They cover the whole thymus, including mesenchyme, endothelium, epithelium, thymocytes, and other lymphocytes. The dataset also includes Drop-seq data on Rag1-/- embryos and on fetal thymic organ cultures (control and a retinoic acid perturbation).
 
Overall design A single-cell atlas of the developing mouse thymus.
 
Contributor(s) Kernfeld E, Genga R, Magaletta M, Neherin K, Xu P, Maehr R
Citation(s) 29884461
NIH grant(s)
Grant ID Grant title Affiliation Name
DP3 DK111898 Deciphering the molecular basis of T1D in human cells using functional genomics President and Fellows of Harvard College Rene Maehr
R01 AI132963 Novel humanized mouse model developed from cord blood CD34 positive HSC and autologous iPS cell derived thymus UNIV OF MASSACHUSETTS MED SCHOOL Rene Maehr
Submission date Dec 11, 2017
Last update date May 15, 2019
Contact name Rene Maehr
Organization name UMass Medical School
Department Program in Molecular Medicine
Lab Diabetes Center of Excellence
Street address 55 Lake Ave N
City Worcester
State/province MA
ZIP/Postal code 01604
Country USA
 
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (27)
GSM2883184 E12_5_wholeThy_venus_1
GSM2883185 E12_5_wholeThy_venus_2
GSM2883186 E12_5_wholeThy_venus_3
Relations
BioProject PRJNA421909
SRA SRP126497

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE107910_RAW.tar 53.3 Mb (http)(custom) TAR (of TXT)
GSE107910_simple_recombinome.fa.gz 15.4 Kb (ftp)(http) FA
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap