|
| Status |
Public on Dec 01, 2017 |
| Title |
Activation of the STING-dependent type I interferon response reduces microglial reactivity and neuroinflammation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
RNA-sequencing analysis of cerebellar microglia from PBS or GCV treated WT or STING goldenticket mice with Experimental Autoimmune Encephalomyelitis (EAE).
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| |
|
| Overall design |
Mice were induced with EAE and GCV treatment started on Day 3 after induction. Mice from each group were sacrificed and microglia isolated when PBS treated mice reached a score of 2 or more.
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| |
|
| Contributor(s) |
Mathur V, Lehallier B, Bonanno LN, Wyss-Coray T |
| Citation(s) |
29268096 |
| |
| Submission date |
Nov 08, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Liana Nicole Bonanno |
| Organization name |
Stanford University
|
| Department |
Neurology
|
| Lab |
Tony Wyss-Coray
|
| Street address |
3801 Miranda Ave, Bldg 100 Rm D3-111
|
| City |
Palo Alto |
| State/province |
California |
| ZIP/Postal code |
94304 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (15)
|
|
| Relations |
| BioProject |
PRJNA417689 |
| SRA |
SRP124637 |
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