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Series GSE106359 Query DataSets for GSE106359
Status Public on Mar 01, 2018
Title Targeted enhancer activation by a subunit of the integrator complex
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary We investigated the genomic occupancy of INTS13 during monocytic differentiation, in in vitro differentiated monocytes and a leukemia-derived cell line. We produced genome wide data for steady state RNA (total RNA-seq) and chromatin-associated RNA (chromatin RNA-seq). Further, we used ChIP-seq to examine genome-wide distribution of INTS13, INTS11, EGR1 and NAB2, as well as the changes in occupancy of RNAPII, H3K4me1 and H3K27ac.
Overall design Analysis of genomic occupancy of INTS13 during monocytic differentiation
Contributor(s) Barbieri E, Trizzino M, Welsh S, Owens T, Gardini A
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Submission date Oct 30, 2017
Last update date May 15, 2019
Contact name Marco Trizzino
Phone 4845983902
Organization name The Wistar Institute
Department Gene expression and regulation
Street address 3601 Spruce street
City Philadelphia
State/province PA
ZIP/Postal code 19104
Country USA
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (53)
GSM2836481 CD34_chromRNA
GSM2836482 HL-60_EGR1_CTRL
GSM2836483 HL-60_EGR1_PMA
BioProject PRJNA416461
SRA SRP123108

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE106359_RAW.tar 11.5 Gb (http)(custom) TAR (of BW)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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