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| Status |
Public on Oct 13, 2017 |
| Title |
Genomic instability induced by furfural-treated in S. cerevisiae [whole genome] |
| Organism |
Saccharomyces cerevisiae |
| Experiment type |
Genome variation profiling by array
Genome variation profiling by SNP array
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| Summary |
Furfural is a key inhibitor in S. cerevisiae fermentation causing serious economic loss. To understand the toxic mechanisms of furfural-induced genomic instability and phenotypic evolution, we mapped chromosomal alterations in 21 furfural-treated yeast strains by whole genome SNP microarrays at a resolution about 1kb.
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| Overall design |
Using whole genome SNP microarrays, we analyzed genomic alterations in 21 yeast strains treated with 2% furfural for 2h repeated for 18 generations to accumulate genomic alterations. For each generation, after furfural treatment, cells were streaked on YPDA plates and cultured at 30 degree for 2 days to form single colony for the next round furfural treatment.
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| Contributor(s) |
Qi L, Zhang K, Zheng D |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Oct 12, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Daoqiong Zheng |
| E-mail(s) |
zhengdaoqiong@163.com
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| Phone |
86 571 88206636
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| Organization name |
College of Life Sciences, Zhejiang University
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| Department |
Institute of Microbiology
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| Street address |
866 Yuhangtang Road
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| City |
Hangzhou |
| State/province |
Zhejiang |
| ZIP/Postal code |
310058 |
| Country |
China |
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| Platforms (1) |
| GPL20144 |
Agilent-027438 Yeast S-Y SNP v1 [Probe Name Version] |
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| Samples (21)
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| This SubSeries is part of SuperSeries: |
| GSE104881 |
Genomic instability induced by furfural-treated in S. cerevisiae |
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| Relations |
| BioProject |
PRJNA414088 |
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