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Series GSE103664 Query DataSets for GSE103664
Status Public on Oct 01, 2018
Title The Estrogen Receptor α (ERα) has stage- and cell type-specific roles in the mammary epithelium with distinct requirements for activation function-1 and -2
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We provide evidence that luminal responder cells express low level ERα required for cell expansion during ductal growth but growth inhibitor during pregnancy.
 
Overall design Intraductally engrafted WT.GFP+ or ERα-/-.GFP+ cells from contralateral glands of the pregnant NSG hosts by FACS sorting for GFP and analysed global gene expression of 3 independent samples by RNA sequencing.
 
Contributor(s) Cagnet S, Ataca D, Sflomos G, Schuepbach-Mallepell S, Aouad P, Hugues H, Krust A, Ayyannan A, Scabia V, Brisken C
Citation(s) 30413705
Submission date Sep 08, 2017
Last update date May 15, 2019
Contact name George A Sflomos
E-mail(s) georgios.sflomos@epfl.ch
Phone 0041(0)216930784
Organization name EPFL
Department ISREC
Lab BRISKEN
Street address SV 2815, Batiment SV, Station 19
City Lausanne
ZIP/Postal code 1024
Country Switzerland
 
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (6)
GSM2778516 ER_WT2
GSM2778517 ER_KO2
GSM2778518 ER_WT3
Relations
BioProject PRJNA403857
SRA SRP117180

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE103664_46h2j3_list_down-regulated_genes_4288.txt.gz 2.9 Kb (ftp)(http) TXT
GSE103664_46h2j3_list_up-regulated_genes_4288.txt.gz 17.1 Kb (ftp)(http) TXT
GSE103664_counts.xlsx 8.4 Mb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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