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Series GSE101689 Query DataSets for GSE101689
Status Public on Sep 19, 2017
Title The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases
Organism Mus musculus
Experiment type Expression profiling by array
Expression profiling by high throughput sequencing
Summary This SuperSeries is composed of the SubSeries listed below.
 
Overall design Refer to individual Series
 
Citation(s) 28930663
NIH grant(s)
Grant ID Grant title Affiliation Name
R01 AG051812 Microglial mechanisms of postoperative CNS inflammation and cognitive decline BRIGHAM AND WOMEN'S HOSPITAL Oleg Butovsky
R01 AG054672 Targeting the miR-155 and APOE-TREM2 pathways to restore dysfunctional microglia in Alzheimer?s disease BRIGHAM AND WOMEN'S HOSPITAL Oleg Butovsky
R01 NS088137 Mechanism of regulation of CNS inflammation by microglia BRIGHAM AND WOMEN'S HOSPITAL Oleg Butovsky
R21 NS101673 Identification of MicroRNA and Proteomics in immune cells and plasma in ALS BRIGHAM AND WOMEN'S HOSPITAL Oleg Butovsky
Submission date Jul 20, 2017
Last update date Jul 25, 2021
Contact name Oleg Butovsky
E-mail(s) obutovsky@rics.bwh.harvard.edu
Phone 1-617-525-5313
Organization name Brigham and Women's Hospital, Harvard Medical School
Department Center of Neurologic Diseases
Lab Dr. Oleg Butovsky
Street address 77 Avenue Louis Pasteur, Office 614
City Boston
State/province MA
ZIP/Postal code 02115
Country USA
 
Platforms (4)
GPL19057 Illumina NextSeq 500 (Mus musculus)
GPL23811 NanoString nCounter Mouse Gene Expression Custom Chip MG468
GPL23812 NanoString nCounter Mouse Gene Expression Custom Chip MG534
Samples (246)
GSM2712028 WTcontrolSOD1_03_score0
GSM2712029 WTcontrolSOD1_02_score0
GSM2712030 SOD1_01_score3
This SuperSeries is composed of the following SubSeries:
GSE101686 The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases I
GSE101687 The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases II
GSE101688 The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases III
Relations
BioProject PRJNA395205

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE101689_RAW.tar 1.1 Mb (http)(custom) TAR (of RCC)
SRA Run SelectorHelp
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