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Series GSE100328 Query DataSets for GSE100328
Status Public on Jun 30, 2018
Title KMT2C medaites the estrogen dependence of breast cancer through regulation of ERα enhancer function
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary KMT2C is a key regulator of ERα activity whose loss allows for hormone independent proliferation in MCF7 cells
Overall design Examination of RNA seq and ChIP seq in cells with KMT2C knockdown as well as cells with KMT2C knockdown that have gorwn out in hormone-deprived media
Contributor(s) Gala K, Chandarlapaty S
Citation(s) 29755131
Submission date Jun 21, 2017
Last update date May 15, 2019
Contact name Kinisha Gala
Organization name Memorial Sloan Kettering Cancer Center
Street address 417 E. 68th Street
City New York
State/province NY
ZIP/Postal code 10065
Country USA
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (47)
GSM2677891 MCF7_shKMT2C#2_CSS_1
GSM2677892 MCF7_shKMT2C#2_CSS_2
GSM2677893 MCF7_shKMT2C#2_CSS_3
BioProject PRJNA391343
SRA SRP110043

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Supplementary file Size Download File type/resource
GSE100328_RAW.tar 7.8 Gb (http)(custom) TAR (of BIGWIG, BW, PNG, TXT)
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Raw data are available in SRA
Processed data provided as supplementary file

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