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| Status |
Public on Nov 13, 2024 |
| Title |
SntB triggers the antioxidant pathways to regulate development and aflatoxin biosynthesis in Aspergillus flavus |
| Organism |
Aspergillus flavus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
In this study, sntB gene deletion (ΔsntB), complementary (Com-sntB), and HA tag fused to snt2 strain (snt2-HA) strains were constructed by using the homologous recombination method, respectively. It was found in this study that SNTB plays a key role in development, secondary metabolism and pathogenicity of A. flavus. The mechanism was explored by Chromatin immunoprecipitation sequencing (ChIP-seq) and RNA sequencing (RNA-seq).
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| Overall design |
To reveal the potential complex regulatory network of the sntB, RNA-seq analysis was carried out on the WT and ΔsntB strains. ChIP-seq analysis was carried out on the WT and sntB-HA strains.
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| |
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| Contributor(s) |
Yang C, Zhuang Z |
| Citation(s) |
39499647 |
| |
| Submission date |
Nov 14, 2023 |
| Last update date |
Nov 13, 2024 |
| Contact name |
Chi Yang |
| E-mail(s) |
2210514010@fafu.edu.cn
|
| Organization name |
Fujian Agriculture and Forestry University
|
| Street address |
No.15 Shangxiadian Road, Cangshan District
|
| City |
Fuzhou |
| ZIP/Postal code |
350014 |
| Country |
China |
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| Platforms (2) |
| GPL30388 |
Illumina NovaSeq 6000 (Aspergillus flavus) |
| GPL33281 |
DNBSEQ-T7 (Aspergillus flavus) |
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| Samples (14)
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| Relations |
| BioProject |
PRJNA1040164 |
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