A Mouse Model for Metabolic Dysfunction-associated Steatotic Liver Disease and Hepatocellular Carcinoma

A first exon termination checkpoint that preferentially suppresses extragenic transcription

A hyper-quiescent chromatin state is a barrier to productive regeneration during aging.

A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS

A trivalent nucleosome interaction by PHIP/BRWD2 is disrupted in neurodevelopmental disorders and cancer

APE1 regulates the transcription of urea cycle genes through stabilizing DNA G-quadruplexes in lung adenocarcinoma

ATAC-seq, ChIP-seq and RNA-seq of in vitro differentiated naïve, Th1, and Th9 cells

An epigenetic pathway regulates MHC-II expression and function in B cell lymphoma models

An in situ method for identification of transcriptome-wide protein-RNA interactions in cells

Antiandrogen treatment endows ZMYDN8 dependent epigenetic reprogramming to orchestrate neuroendocrine tumor transdifferentiation

Autonomous transposons tune their sequences to ensure somatic suppression.

BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state

BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state

CPSF6-RARγ Interacts with HDAC3 to Promote Myeloid Transformation

CaBl: MSL2 is an allelic dosage sensor in mammals

Cancer associated fibroblasts play an important role in prostate cancer progression

Chromatin architecture of B cell development during the humoral immune response

Chromatin opening by p53 is confined by Trim24 in a histone methylation-dependent manner

Co-repressor CDYL confers forebrain identity to human cortical organoids by negatively regulating NNAT

Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B-cell fate decisions and accelerates development of T-cell depleted lymphomas.