The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis

UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells

Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease

HOXBLINC is aberrantly expressed in acute myeloid leukemia and functions as a potent oncogenic long non-coding RNA in leukemogenesis

H3K36me2 recruits DNMT3A and shapes intergenic DNA methylation landscapes

A neutropenia-associated transcription factor mutation differentially impacts target genes in the cell-states traversed during granulocyte specification and commitment

Chromatin accessibility landscape upon induction of Msgn1, Pax3 and Myf5 in mesodermal cells and identification of conserved Pax3 binding sites and target genes during skeletal myogenesis

Comparative transcriptome profiling myometrial and vascular smooth muscle cells

Single-cell multi-omic integration compares and contrasts features of brain cell identity

Genome-wide methyl-cytosine competition by DNMT and TET

Spatially patterned scaffolds enhances vascular organization and functional integration in volumetrc muscle loss

Replicational dilution of H3K27me3 in mammalian cells and the role of poised promoters

MAFG-driven astrocytes promote CNS inflammation

Combined Cohesin-Runx1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes

Intratumoral TFR cells curtail anti-PD-1 treatment efficacy

Loss of ATF4 leads to functional aging-like attrition of adult hematopoietic stem cells

Senescence rather than apoptosis of alveolar progenitor cells drives pulmonary fibrosis

A first exon termination checkpoint that preferentially suppresses extragenic transcription

The Evolving Immune Microenvironment of Human B-cell Acute Lymphoblastic Leukemia

Nutrient regulation of the islet epigenome controls adaptive insulin secretion