Non-Canonical PRC1.1 is required for the activity of Menin-MLL1 Inhibitors in NUP98-Rearranged AML [RNA-seq]

CUT&Tag, ATAC-seq, bulk RNA-seq and single-nucleus RNA-seq analysis of histone variant H2BE in cortical neurons

Mediator Complex Subunit 1 Promotes Differentiation and Function of a Tumor-Specific T Regulatory Cell Population

Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation

Deletion of a state-specific PD-1 enhancer modulates exhausted T cell fate and function

A lncRNA identifies Irf8 enhancer element in negative feedback control of dendritic cell differentiation

YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation

Pharmacological inhibition of CDK4/6 augments long-term anti-tumor immunity through the induction of T cell memory

Pharmacological inhibition of CDK4/6 augments long-term anti-tumor immunity through the induction of T cell memory [13_RNAseq_in_vitro_mouse]

Pharmacological inhibition of CDK4/6 augments long-term anti-tumor immunity through the induction of T cell memory [12_RNAseq_in_vitro_mouse_rb_and_thy]

Pharmacological inhibition of CDK4/6 augments long-term anti-tumor immunity through the induction of T cell memory [11_RNAseq_in_vitro_mouse_HER2_CAR]

Pharmacological inhibition of CDK4/6 augments long-term anti-tumor immunity through the induction of T cell memory [8_RNAseq_ex_vivo_mouse]

Chromatin state changes induced by targeted degradation of MLL-AF9 are phenocopied by combined DOT1L and MENIN inhibition.

Chromatin state changes induced by targeted degradation of MLL-AF9 are phenocopied by combined DOT1L and MENIN inhibition. [RNA-Seq]

Impact of heterozygous SRI mutation (R2483H) of Setd2 (Setd2SRI/wt)

Neuronal Nsun2 deficiency is associated with codon-specific epitranscriptomic dysregulation of Gly-tRNAs and corresponding proteomic shift impacting synaptic signaling and behavior

Stat1 activation, through systemic interferon signaling, and upregulation of innate immune system receptors drives inflammaging, that is ameliorated by dietary restriction intervention

The catalytic domain of the histone methyltransferase NSD2/MMSET is required for the generation of B1 cells in mice

Characterization of chromatin and gene expression changes during fasting and refeeding in mouse liver

FUBP1 and FUBP2 enforce distinct epigenetic setpoints for MYC expression in primary single murine cells