A transcriptomic taxonomy of mouse brain-wide spinal projecting neurons

The expression order determines the pioneer functions of Ngn3 and NeuroD1 in pancreatic endocrine differentiation

Cardiac fibroblasts regulate the development of heart failure via Htra3-TGF-β-IGFBP7 axis

T cell - DAM feedback loop drives CNS inflammation and neurodegenration in SPG15 at an early age

Tabula Muris

Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop

LGR5 expressing skin fibroblasts define a major hub perturbed in Systemic Sclerosis

Stromal niche inflammation mediated by IL-1 signaling is a targetable driver of hematopoietic aging

Single-Cell Resolution of Lineage Trajectories in the Arabidopsis Stomatal Lineage and Developing Leaf

Regulation of intestinal immunity and tissue repair by enteric glia

Donor regulatory T cells rapidly adapt to recipient tissues to control acute graft-versus-host disease

Epigenomics Studies in Acute Myeloid Leukemia disease progression

Age-dependent immune and lymphatic responses after spinal cord injury

Hypermitotic meningiomas harbor DNA methylation subgroups with distinct biological and clinical features

Multi-omics and 3D-imaging reveal bone heterogeneity and unique calvaria cells in neuroinflammation

APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFbeta-mediated checkpoints

Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity

Predicting age in single cells and low coverage DNA methylation data

Affinity maturation broadens influenza vaccine-induced antibody responses in humans

A single-cell atlas of immune heterogeneity in anti-PD1-treated non-small cell lung cancer